Cancer: The Possibilities

Cancer epidemiology: shortcomings and possibilities.

The development of the concepts of initiators and promoters in carcinogenesis necessitates deliberations of evidence from human cancer epidemiology. Recent arguments in favor of mortality data as a more reliable indicator of trends in cancer incidence than morbidity data collected from cancer registries are disputed. Inconsistency in the use of data is pointed out. Comparisons of data from canc...

Possibilities of the Philosophy of History

Metastatic Colorectal Cancer: Lessons Learned, Future Possibilities.

Survival of patients with metastatic colorectal cancer has dramatically improved over the past 20 years, primarily because physicians have become adept at using the many regimens approved for this patient population. Future advances may come from understanding molecular subtypes, finding and treating new actionable mutations, and harnessing the immune system.

New possibilities in chemotherapy for colorectal cancer.

Colorectal cancer is the second leading cause of cancer death. Approximately 26,000 new cases are diagnosed yearly in France, resulting in more than 10,000 deaths, and 5-year survival remains low, at 40%. This poor prognosis is partly due to the fact that, in 30% of cases, colorectal cancer is metastatic or at a locally advanced stage when discovered. Moreover, visceral metastases complicate th...

Surgical possibilities for pancreatic cancer: extended resection.

DESIGN It was the aim of this study to investigate the influence of extended retroperitoneal tissue clearance on long-term survival in patients with ductal adenocarcinoma of the head of the pancreas. PATIENTS AND METHODS From 10/1988 to 3/1998 a prospective observation study was initiated in 108 patients with malignant growth in the head of the pancreas to compare patients with regional lymph...